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Phthalate and non-phthalate plasticizers in indoor dust from childcare facilities, salons, and homes across the USA

机译:邻苯二甲酸酯和非邻苯二甲酸酯增塑剂在室内灰尘中,来自美国儿童保育设施,沙龙和美国的家园

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摘要

The quality of indoor environment has received considerable attention owing to the declining outdoor human activities and the associated public health issues. The prolonged exposure of children in childcare facilities or the occupational exposure of adults to indoor environmental triggers can be a culprit of the pathophysiology of several commonly observed idiopathic syndromes. In this study, concentrations of potentially toxic plasticizers (phthalates as well as non-phthalates) were investigated in 28 dust samples collected from three different indoor environments across the USA. The mean concentrations of non-phthalate plasticizers [acetyl tri-n-butyl citrate (ATBC), di-(2-ethylhexyl) adipate (DEHA), and diisobutyl adipate (DIBA)] were found at 0.51e880 mg/g for the first time in indoor dust samples from childcare facilities, homes, and salons across the USA. The observed concentrations of these replacement non-phthalate plasticizer were as high as di-(2-ethylhexyl) phthalate, the most frequently detected phthalate plasticizer at highest concentration worldwide, in most of the indoor dust samples. The estimated daily intakes of total phthalates (n = 7) by children and toddlers through indoor dust in childcare facilities were 1.6 times higher than the non-phthalate plasticizers (n = 3), whereas estimated daily intake of total non-phthalates for all age groups at homes were 1.9 times higher than the phthalate plasticizers. This study reveals, for the first time, a more elevated (~3 folds) occupational intake of phthalate and non-phthalate plasticizers through the indoor dust at salons (214 and 285 ng/kg-bw/day, respectively) than at homes in the USA.
机译:室内环境质量已经收到由于户外下降人类活动和相关的公共卫生问题相当重视。儿童的保育设施的长期接触或成人职业暴露于室内环境触发器可以是几种常见的特发性观察综合症的病理生理的罪魁祸首。在这项研究中,潜在有毒的增塑剂(邻苯二甲酸酯,以及非邻苯二甲酸酯)的浓度在来自整个美国三个不同的室内环境中收集28个尘埃样本进行了研究。非邻苯二甲酸酯增塑剂的平均浓度[乙酰基三正丁酯,柠檬酸酯(ATBC),二 - (2-乙基己基)己二酸酯(DEHA),和己二酸二异丁酯(DIBA)]在0.51e880毫克/克被发现的所述第一从时间托儿设施,家庭和整个美国美发室内灰尘样品英寸这些更换非邻苯二甲酸酯增塑剂的观测到的浓度高达二 - (2-乙基己基)邻苯二甲酸酯,最频繁地检测邻苯二甲酸酯增塑剂在全球范围内的浓度最高,在大多数室内灰尘样品。总的邻苯二甲酸酯的估计每日摄入量(N = 7)通过在保育设施室内灰尘儿童和学步孩童分别为1.6倍高于非邻苯二甲酸酯增塑剂(N = 3),而估计每日摄入的总的非邻苯二甲酸酯的适于各种在家庭组均高于邻苯二甲酸酯增塑剂高1.9倍。这项研究揭示,对于第一次,更升高(约3倍)的职业进邻苯二甲酸酯和非邻苯二甲酸酯增塑剂的通在美发室内灰尘(214和285纳克/ kg体重/天,分别地)比在家庭美国。

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