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Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System

机译：纳米金属颗粒作为靶向药物输送系统中的纳米载体

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摘要

In the recent years, noble metal particles such as gold (Au) and silver (Ag) have been used progressively as efficient and safe nanoscale drug carriers in treating malignant as cites of cancerous cells. These single crystal structures of functionalised thearapeutic particles with the size less than 100 nm in diameter had proven offered an excellent function to modulate the oxidative stress and toxicity at affected membrane cells particularly to achieve the site-specific delivery of drugs. This mini-review will highlight the current advances of Au and Ag nanoscale particles as smart chemotherapeutic molecule carriers to these malignancies in impeding cancer cell activities locally. The paper also reviewed valuable insights of their efficacy in maintaining and precisely control the drugs udrelease level within the therapeutic windows.
机译：近年来，诸如金（Au）和银（Ag）之类的贵金属颗粒已被逐步用作治疗恶性癌细胞的有效且安全的纳米级药物载体。直径小于100 nm的功能化治疗性颗粒的这些单晶结构已被证明具有出色的功能，可调节受影响的膜细胞的氧化应激和毒性，特别是实现针对部位的药物递送。这份小型综述将重点介绍金和银纳米级颗粒作为智能化学治疗分子载体对恶性肿瘤在局部阻碍癌细胞活性方面的最新进展。本文还回顾了其在治疗窗口内维持和精确控制药物释放水平的功效的宝贵见解。

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