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首页> 外文OA文献 >Immunohistochemical expression of matrilysins (MMP-7 and MMP-26) in ameloblastomas and adenomatoid odontogenic tumors
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Immunohistochemical expression of matrilysins (MMP-7 and MMP-26) in ameloblastomas and adenomatoid odontogenic tumors

机译：基质细胞溶解素（MMP-7和MMP-26）在成纤维细胞瘤和腺样牙源性牙源性肿瘤中的免疫组织化学表达

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OBJECTIVE:The aim was to evaluate the expression of matrix metalloproteinases (MMPs) 7 and 26 in ameloblastomas and adenomatoid odontogenic tumors (AOTs).STUDY DESIGN:Twenty intraosseous solid ameloblastomas and 10 intraosseous AOTs were evaluated regarding immunohistochemical expression of MMP-7 and -26 in the epithelium and stroma.RESULTS:There was no statistically significant difference in MMP-7 and -26 expression between the epithelium of ameloblastomas (P = .50) and AOTs (P = .90). Stromal staining for MMP-7 was evident in all cases. For MMP-26, stromal staining was observed in 65% of ameloblastomas and 50% of AOTs, and this difference was not statistically significant (P = .69).CONCLUSION:The marked expression of these matrilysins suggests their role in the process of tissue remodeling and growth in the studied tumors, but it does not relate to the their distinct patterns of aggressiveness.
机译：目的：评估成釉细胞瘤和腺瘤样成牙本质肿瘤（AOT）中基质金属蛋白酶（MMPs）7和26的表达。研究设计：评估20例骨内实体成纤维细胞瘤和10例骨内AOTs对MMP-7的免疫组织化学表达，以及-结果：成纤维细胞瘤上皮（P = .50）和AOT（P = .90）之间的MMP-7和-26表达在统计学上无显着差异。在所有情况下，MMP-7的基质染色都很明显。对于MMP-26，在65％的成纤维细胞瘤和50％的AOT中观察到基质染色，并且这种差异在统计学上无统计学意义（P = 0.69）。结论：这些基质溶素的明显表达表明它们在组织过程中的作用在所研究的肿瘤中重塑和生长，但与它们的不同侵袭性模式无关。

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