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首页> 外文OA文献 >The sensitivity and specificity of subjective memory complaints and the subjective memory rating scale, deterioration cognitive observee, mini-mental state examination, six-item screener and clock drawing test in Dementia Screening.
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The sensitivity and specificity of subjective memory complaints and the subjective memory rating scale, deterioration cognitive observee, mini-mental state examination, six-item screener and clock drawing test in Dementia Screening.

机译：主观记忆投诉的敏感性和特异性以及痴呆筛查中的主观记忆评定量表，恶化认知观察，迷你精神状态检查，六项筛选和时钟绘图测试。

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Background: The effectiveness of dementia screening depends on the availability of suitable screening tools with good sensitivity and specificity to confidently distinguish normal age-related cognitive decline from dementia. The aim of this study was to evaluate the discriminant validity of 7 screening measures for dementia. Methods: A sample of 140 participants aged ≥60 years living in a residential facility for the aged were assessed clinically and assigned caseness for dementia using the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revised diagnostic criteria. Sensitivity and specificity of a selection of the following screening measures were tested using receiver operating characteristic (ROC) analysis for individual and combined tests: the Mini-Mental State Examination (MMSE), Six-Item Screener (SIS), Subjective Memory Complaint, Subjective Memory Complaint Clinical (SMCC), Subjective Memory Rating Scale (SMRS), Deterioration Cognitive Observee (DECO) and the Clock Drawing Test (CDT). Results: Using ROC analyses, the SMCC, MMSE and CDT were found to be ‘moderately accurate' in screening for dementia with an area under the curve (AUC) >0.70. The AUCs for the SIS (0.526), SMRS (0.661) and DECO (0.687) classified these measures as being ‘less accurate'. At recommended cutoff scores, the SMCC had a sensitivity of 90.9% and specificity of 45.7%; the MMSE had a sensitivity of 63.6% and a specificity of 76.0%, and the CDT had a sensitivity of 44.4% and a specificity of 88.9%. Combining the SMCC and MMSE did not improve their predictive power except for a modest increase when using the sequential rule. Conclusion: The SMCC is composed of valid screening questions that have high sensitivity, are simple to administer and ideal for administration at the community or primary health care level as a first level of ‘rule-out' screening. The MMSE can be included at a second stage of screening at the general hospital level and the CDT in specialist clinical settings. Sequential use of the SMCC and MMSE will improve the specificity of the former and the sensitivity of the latter.
机译：背景：痴呆症筛查的有效性取决于是否具有合适的筛查工具，这些筛查工具具有良好的敏感性和特异性，可以可靠地区分正常的年龄相关性认知功能下降与痴呆症。这项研究的目的是评估对痴呆症的7种筛查措施的判别有效性。方法：使用《精神疾病诊断和统计手册》第4版，经文本修订的诊断标准，对140例年龄≥60岁，居住在老年人设施中的参与者进行了临床评估，并确定了痴呆症的病情。使用接收器工作特征（ROC）分析对以下各项筛选方法的敏感性和特异性进行了单独和组合测试：最小精神状态检查（MMSE），六项检查器（SIS），主观记忆投诉，主观记忆投诉临床（SMCC），主观记忆评估量表（SMRS），认知退化观察（DECO）和时钟绘图测试（CDT）。结果：使用ROC分析，发现SMCC，MMSE和CDT在筛查痴呆症时具有“中等准确度”，曲线下面积（AUC）> 0.70。 SIS（0.526），SMRS（0.661）和DECO（0.687）的AUC将这些量度归类为“不太准确”。在推荐的临界值上，SMCC的敏感性为90.9％，特异性为45.7％； MMSE的敏感性为63.6％，特异性为76.0％，CDT的敏感性为44.4％，特异性为88.9％。将SMCC和MMSE结合起来并不会提高其预测能力，只是在使用顺序规则时适度增加。结论：SMCC由有效的筛查问题组成，这些筛查问题具有很高的敏感性，易于管理，非常适合在社区或基层医疗机构中作为“排除”筛查的第一级进行管理。 MMSE可以包括在综合医院级别的第二阶段筛查中，而在专业临床环境中则包括CDT。依次使用SMCC和MMSE将提高前者的特异性和后者的敏感性。

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