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Whole-body vibration training effect on physical performance and obesity in mice

机译：Whole-body vibration training effect on physical performance and obesity in mice

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The purpose of this study was to verify the beneficial effects of whole-body vibration (WBV) training on exercise performance, physical fatigue and obesity in mice with obesity induced by a high-fat diet (HFD). Male C57BL/6 mice were randomly divided into two groups: normal group (n=6), fed standard diet (control), and experimental group (n=18), fed a HFD. After 4-week induction, followed by 6-week WBV of 5 days per week, the 18 obese mice were divided into 3 groups (n=6 per group): HFD with sedentary control (HFD), HFD with WBV at relatively low-intensity (5.6 Hz, 0.13 g) (HFD+VL) or high-intensity (13 Hz, 0.68 g) (HFD+VH). A trend analysis revealed that WBV increased the grip strength in mice. WBV also dose-dependently decreased serum lactate, ammonia and CK levels and increased glucose level after the swimming test. WBV slightly decreased final body weight and dose-dependently decreased weights of epididymal, retroperitoneal and perirenal fat pads and fasting serum levels of alanine aminotransferase, CK, glucose, total cholesterol and triacylglycerol. Therefore, WBV could improve exercise performance and fatigue and prevent fat accumulation and obesity-associated biochemical alterations in obese mice. It may be an effective intervention for health promotion and prevention of HFD-induced obesity.
机译：这项研究的目的是验证全身振动（WBV）训练对高脂饮食（HFD）诱发的肥胖小鼠的运动表现，身体疲劳和肥胖的有益作用。将雄性C57BL / 6小鼠随机分为两组：正常组（n = 6），喂食标准饮食（对照组），实验组（n = 18），喂食HFD。诱导4周后，随后每周进行5天的6周WBV，将这18只肥胖小鼠分为3组（每组n = 6）：久坐控制（HFD）的HFD，相对低血糖的WBV的HFD-强度（5.6 Hz，0.13 g）（HFD + VL）或高强度（13 Hz，0.68 g）（HFD + VH）。趋势分析显示，WBV可增加小鼠的抓地力。游泳试验后，WBV还剂量依赖性地降低血清乳酸，氨和CK水平，并增加葡萄糖水平。 WBV使最终体重略有下降，附睾，腹膜后和肾周脂肪垫的重量与剂量相关地降低，并且空腹血清丙氨酸转氨酶，CK，葡萄糖，总胆固醇和三酰基甘油的水平。因此，WBV可以改善肥胖小鼠的运动表现和疲劳，并防止脂肪堆积和肥胖相关的生化改变。它可能是促进健康和预防HFD引起的肥胖的有效干预措施。

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