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一种应用于小分子定性定量分析检测和高通量筛选常规水容易样品试剂盒及其制备

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摘要

一种应用于小分子定性定量分析检测和高通量筛选常规水容易样品试剂盒及其制备，将水溶液样本放置室温，充分解冻；加入-20度同等体积的混合溶液-基本裂解液QL4，在50度水浴中反应5分钟；离心，收集上清液；QL4物质组成及体积比为：50-100％甲醇，体积比1-7％的甲酸，此试剂盒制备方法简单、成本较低。

著录项

公开/公告号CN104237425A

专利类型发明专利
公开/公告日2014-12-24

原文格式PDF
申请/专利权人武汉品生科技有限公司;
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申请/专利号CN201410453831.4
发明设计人成晓亮;郑可嘉;
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申请日2014-09-09
分类号G01N30/06;G01N30/72;
代理机构南京知识律师事务所;
代理人胡玲
地址 430040 湖北省武汉市东西湖区七雄路海峡创业城二期1栋303
入库时间 2023-12-17 04:27:34

法律信息

法律状态公告日

法律状态信息

法律状态
2018-04-06

发明专利申请公布后的驳回 IPC(主分类):G01N30/06 申请公布日:20141224 申请日:20140909

发明专利申请公布后的驳回
2015-01-14

实质审查的生效 IPC(主分类):G01N30/06 申请日:20140909

实质审查的生效
2014-12-24

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公开

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1. 一种应用于小分子定性定量分析检测和高通量筛选常规水容易样品试剂盒及其制备 [P] . 中国专利： CN104237425A . 2014-12-24
2. 一种应用于小分子定性定量分析检测和高通量筛选细胞培养液样品试剂盒及其制备 [P] . 中国专利： CN104215684A . 2014-12-17
3. Polinucleotu00eddeo insulated tape of expression, host cell, isolated transgenic non-human animal polypeptide, which has been modified to express a polypeptide mutant with resistance to ALK, antibody that binds specifically to a polypeptide mutant with resistance to ALK, kit p For detection of a mutation with resistance to ALK inhibitor in a biological sample, and,Methods for evaluating a biological sample as a mutation with resistance to ALK inhibitor, for diagnosing a cancer that is resistant to or is likely to develop resistance to at least one inhibitor of kinase small molecule ALK, to evaluate a biological sample that Anto a mutation with resistance to ALK inhibitor.For diagnosing a cancer that is resistant to or is likely to develop resistance to at least one inhibitor of kinase small molecule ALK, to assess the biological sample as a mutation with resistance to ALK inhibitor, a cancer that is resistant to dianosticar Or is likely to develop resistance to PF - 02341066 in a pati [P] . BR112012026239A2 . 2016-11-29

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4. isolated polynucleotide, expression cassette, host cell, isolated polypeptide, non-human transgenic animal that has been altered to express an alkali resistant mutant polypeptide, an antibody that specifically binds to an alkali resistant mutant polypeptide, a mutation detection kit alk inhibitor resistance in a biological sample, and methods for evaluating a biological sample for an alk inhibitor resistance mutation to diagnose cancer that is resistant to or likely to develop resistance to at least one alkaline inhibitor. small alk molecule kinase, to evaluate a biological sample for an alk inhibitor resistance mutation, to diagnose cancer that is resistant to or likely to develop resistance to pf-02341066 in a patient, to specifically reduce expression of an alk-resistant mutant to treat cancer associated with activating aberrant loop capacity that is resistant to at least one small molecule alk kinase inhibitor treating an aberrant cancer that is resistant to pf-02341066, identifyin [P] . BR112012026239A2 . 2018-06-26

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机译：一种制备用于核酸扩增的所有细胞含量样品的方法以及扩增靶标的核酸分子的方法，即制备一种用于试剂盒无效核酸扩增的所有细胞含量样品的方法。