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一种用于鉴定宫颈癌易感性的检测试剂盒

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摘要

本发明公开了一种用于鉴定宫颈癌易感性的检测试剂盒，属于分子生物学与生物医药技术领域。检测试剂盒中具有基于hOGG1基因单核苷酸多态性设计的两对特异性引物，核苷酸序列如SEQ ID NO.1所示分子标记的第7146位存在单核苷酸多态性：C>G。hOGG1基因单核苷酸多态性rs1052133(C>G)与宫颈癌易感性密切相关。利用PCR技术可以有效检测hOGG1基因中的单核苷酸多态性，该方法检测简单、快捷、特异性高，同时费用低廉、无需特殊的DNA测序设备，便于在各级临床医院推广应用，这对于宫颈癌高危人群的筛选和易感个体的检测，对宫颈癌这个复杂性疾病进行早期预防、早期诊断和个性化防治具有重要的现实意义。

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公开/公告号CN109355386B

专利类型发明专利
公开/公告日2021-05-25

原文格式PDF
申请/专利权人浙江大学;
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申请/专利号CN201811412825.9
发明设计人陈怀增;叶枫;王浛知;程琪;马俊彦;陈晓静;
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申请日2018-11-23
分类号C12Q1/6886(20180101);
代理机构33224 杭州天勤知识产权代理有限公司;
代理人韩聪
地址 310013 浙江省杭州市西湖区余杭塘路866号
入库时间 2022-08-23 11:50:36

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1. 一种用于鉴定宫颈癌易感性的检测试剂盒 [P] . 中国专利： CN109355386B . 2021.05.25
2. 一种鉴定宫颈癌遗传易感性的检测试剂盒 [P] . 中国专利： CN109355388B . 2021.08.24
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机译：快速检测和鉴定样品中一种或多种目标微生物的方法;一种用于快速检测和鉴定牡蛎中生活的一种或多种目标微生物的设备;用于快速检测和鉴定样品中生活的一种或多种目标微生物的检测试剂盒，用于该方法。
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机译：一种鉴定参与脂质调节的分子和蛋白质的方法，测试一种物质作为调节脂质水平的治疗剂，治疗脂质介导的疾病和患有脂质介导的疾病的患者，治疗宿主的脂质水平或预防脂质介导的疾病，治疗或预防动脉粥样硬化或与动脉粥样硬化有关的疾病，筛选诊断动脉粥样硬化的遗传易感性或与动脉粥样硬化或脂质介导的疾病有关的疾病，在组织中表达hbm蛋白并调节患者中的脂质水平，确定脂质介导疾病易感性的诊断测定法，用于治疗脂质介导疾病的组合物以及用于治疗患有疾病或脂质介导疾病的患者的联合疗法
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