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Composition for preventing or treating cancer containing Triazolopyridine-based derivative as active ingredient
Composition for preventing or treating cancer containing Triazolopyridine-based derivative as active ingredient
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机译:含有三唑并吡啶类衍生物作为有效成分的预防或治疗癌症的组合物
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摘要
The present invention relates to a composition for preventing or treating cancer containing a triazolopyridine-based derivative or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the triazolopyridine-based derivative inhibits tankyrase enzyme activity to suppress the expression of β-catenin, which is a tumor factor, thereby increasing cancer cell death by apoptosis. Due to exhibiting excellent survival rate reduction when used in combination with anti-cancer drugs or irradiation, the triazolopyridine-based derivative can be usefully used as a pharmaceutical composition for preventing and treating cancer, a composition for increasing the effect of radiation therapy, or a health functional food for preventing or improving cancer.
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