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METHOD OF COMBINED LIVER CANCER PC-1 THERAPY IN EXPERIMENT

机译:实验中联合肝癌PC-1治疗的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to experimental medicine and oncology, and can be used for combined therapy of liver cancer PC-1 in experiment. Method involves the daily introduction of cyclophosphamide in dose of 5 mg/kg for 3 weeks. Not earlier than 30 minutes later and not later than 45 minutes from the administration of cyclophosphamide, intraperitoneal introduction of a solution of gratiole extract daily in dose of 110 mg/kg.;EFFECT: use of the invention enables to potentiate anticancer effects of said substances in 2_6 times compared to separate use of cyclophosphamide, as well as a favorable effect on the body of laboratory animals with tumor, promotes body weight gain, prevents development of cachexia due to reduced toxicity by gratiole extract used in combination of cyclophosphamide, and reduced toxic effect of disintegration and tumor necrosis.;1 cl, 1 ex, 5 dwg
机译:技术领域本发明涉及医学,即实验医学和肿瘤学,可用于实验中肝癌PC-1的联合治疗。该方法涉及每天以5 mg / kg的剂量连续3周每天引入环磷酰胺。施用环磷酰胺后不迟于30分钟且不迟于45分钟,每天腹膜内以110 mg / kg的剂量腹膜内注射鹰嘴豆提取物溶液;效果:本发明的使用能够增强所述物质的抗癌作用与单独使用环磷酰胺相比,效果提高了2_6倍,并且对患有肿瘤的实验动物的身体具有良好的作用,可促进体重增加,防止由于环磷酰胺组合使用的格拉格雷提取物的毒性降低了恶病质的发展,并降低了毒性崩解和肿瘤坏死的影响。; 1 cl,1 ex,5 dwg

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