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METHOD FOR PREDICTION OF SEVERE POST-EMBOLIZATION SYNDROME IN PATIENT WITH UTERINE MYOMA IN EARLY POSTOPERATIVE PERIOD

机译:早期手术后子宫肌瘤患者严重血栓后综合征的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to obstetrics and gynecology, and can be used in predicting severe course post-embolization syndrome (PES) in women in early postoperative period after uterine myoma embolization. A method for prediction of severe clinical course of post-embolization syndrome in patients with hysteromyoma in the early postoperative period, characterized by the fact that such prognostic parameters as skin microcirculation indices – endothelial (E) and respiratory (R) oscillations of microcirculation are determined by laser Doppler flowmetry in conducting an occlusion test in females with hysteromyoma and additionally determining body weight index (BWI), in the period preceding surgical treatment by uterine artery embolization, wherein endothelial oscillations (E) and respiratory oscillations (R) are measured in perfusion units (pf units), and the index body weight = weight/height is measured in kg/m2, wherein each risk factor after its measurement and wavelet transformation (E, R) or calculation of body weight index is multiplied by a regression coefficient (b), value of which for endothelial oscillations (E) is (-2.50); for respiratory oscillations (R) is 12.69; for body weight index is (-0.21); obtained digital values are summed up with adding to the obtained sum constant (6.67), thus at the first stage the value of intermediate value "z" is obtained by formula: z=[(-2.50⋅E)+(12.69⋅R)+(-0.21⋅BWI)]+6.67, where 6.67 is a constant; at the second stage, calculating a probability of developing a severe post-embolization syndrome by a logistic regression formula p=ez(1+ez), where p is a prognostic coefficient, wherein the value of the prognostic coefficient is greater than or equal to 0.25, the probability of developing a severe postembolization syndrome is high, and if the prognostic coefficient is less than 0.25, uterine myoma is referred to the low-risk group of severe postembolization syndrome.;EFFECT: method enables detecting groups of high risk of developing severe post-embolization syndrome in early postoperative period, increase reliability, information value, provide timely diagnosis of risk factors of severe post-embolization syndrome and complications after UAE, as well as ensure timely appointment of optimal treatment and management of patients in early postoperative period aimed at preventing and reducing the risk of developing complications following uterine artery embolization.;1 cl, 2 tbl, 1 ex
机译:技术领域本发明涉及医学,即涉及妇产科,可用于预测子宫肌瘤栓塞术后早期妇女严重栓塞后综合症(PES)。一种预测子宫肌瘤患者术后早期栓塞后综合症严重临床病程的方法,其特征在于确定诸如皮肤微循环指标(微循环的内皮(E)和呼吸(R))的预后参数通过激光多普勒血流仪在子宫肌瘤女性中进行闭塞试验并另外确定体重指数(BWI),在通过子宫动脉栓塞进行手术治疗之前,其中在灌注时测量内皮振荡(E)和呼吸振荡(R)单位(pf单位),并且指数体重=体重/身高以kg / m 2 为单位,其中每个风险因素经过测量和小波变换(E,R)或体重计算后得出指数乘以回归系数(b),对于内皮振荡(E),其值为(-2.50);呼吸振荡(R)为12.69;体重指数为(-0.21);将获得的数字值加到获得的总常数(6.67)上进行求和,因此,在第一阶段,通过公式z = [(-2.50⋅E)+(12.69⋅R)获得中间值“ z”的值+(-0.21⋅BWI)] + 6.67,其中6.67是常数;在第二阶段,通过对数回归公式p = e z (1 + e z )计算发生严重栓塞后综合症的概率,其中p为a预后系数,其中预后系数的值大于或等于0.25,发生严重栓塞后综合症的可能性高,如果预后系数小于0.25,则子宫肌瘤被称为低风险组严重:后栓塞综合征;效果:该方法能够在术后早期检测出发生严重栓塞后综合征的高风险人群,提高可靠性,信息价值,并及时诊断出严重栓塞后综合征和阿联酋术后并发症的危险因素,例如并确保在术后早期及时安排患者的最佳治疗和管理,以预防和减少子宫动脉栓塞后发生并发症的风险。; 1 cl,2 tbl,1前

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