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Improved system for expressing cancer antigens to antigen-expressing cells by cancer immunotherapy by radiofrequency electrical membrane breakdown (RF-EMB) as an adjuvant mechanism for immunotherapy
Improved system for expressing cancer antigens to antigen-expressing cells by cancer immunotherapy by radiofrequency electrical membrane breakdown (RF-EMB) as an adjuvant mechanism for immunotherapy
A method of non-thermal ablation of unwanted cells in the body is disclosed which results in complete and immediate membrane rupture and destruction by applying a bipolar pulse of an instantaneous charge inversion electric field of sufficient energy. Energy is transmitted through high-frequency pulses with a specific frequency, wave characteristics, pulse width and number of pulses, and more enhanced physical stress acts on the cell membrane, which causes immediate and complete destruction of the cell membrane, thereby destroying all cell contents and membrane components. Proteins are released into the extracellular space without denaturing, thereby allowing the immune response to destroy and remove similarly labeled tissues in target tissues and other sites within the subject.
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