首页> 外国专利> miR-605 AG miR-608 GC miR-631 ID miR-938 CT miR-1302-3 CT Association of miR-605 AG miR-608 GC miR-631 ID miR-938 CT and miR-1302-3 CT polymorphism with the risk of recurrent implantation failure in a Korean women

miR-605 AG miR-608 GC miR-631 ID miR-938 CT miR-1302-3 CT Association of miR-605 AG miR-608 GC miR-631 ID miR-938 CT and miR-1302-3 CT polymorphism with the risk of recurrent implantation failure in a Korean women

机译:miR-605 AG miR-608 GC miR-631 ID miR-938 CT miR-1302-3 CT miR-605 AG miR-608 GC miR-631 ID miR-938 CT和miR-1302-3 CT多态性与韩国女性反复植入失败的风险

摘要

The present invention relates to a correlation between miR-605 A G (rs2043556), miR-608 G C (rs4919510), miR-631 I D (rs5745925), miR-938 C T (rs12416605) and miR-1302-3 C T (rs7589328) polymorphisms and a risk of recurrent implantation failures among Korean women and, more particularly, to a method and a kit for distinguishing the polymorphism from a subject′s DNA sample to provide information required for predicting a risk of developing recurrent implantation failures among Korean women. According to the present invention, it is possible to provide information very useful in predicting a risk of developing recurrent implantation failures among Korean women by distinguishing a polymorphism of the subject′s microRNA-related gene. In particular, in case of using the kit of the present invention using the polymorphism, it is possible to more easily provide the above information.
机译:本发明涉及miR-605 A> G(rs2043556),miR-608 G> C(rs4919510),miR-631 I> D(rs5745925),miR-938 C> T(rs12416605)和miR- 1302-3 C> T(rs7589328)多态性与韩国女性中反复植入失败的风险,尤其是一种从受试者的DNA样本中区分多态性以提供预测风险所需信息的方法和试剂盒女性复发性植入失败的原因。根据本发明,通过区分受试者的microRNA相关基因的多态性,可以提供非常有用的信息,以预测在韩国女性中发生复发性植入失败的风险。特别地,在使用具有多态性的本发明的试剂盒的情况下,可以更容易地提供上述信息。

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