首页>
外国专利>
miR27a AG miR423 CA miR449b AG miR604 AG Association of miR27a AG miR423 CA miR449b AG and miR604 AG single nucleotide polymorphism with the risk of recurrent implantation failure in a Korean women
miR27a AG miR423 CA miR449b AG miR604 AG Association of miR27a AG miR423 CA miR449b AG and miR604 AG single nucleotide polymorphism with the risk of recurrent implantation failure in a Korean women
展开▼
机译：miR27a AG miR423 CA miR449b AG miR604 AG miR27a AG miR423 CA miR449b AG和miR604 AG单核苷酸多态性与韩国女性反复植入失败的风险
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention miR-27a AG (rs895819), miR-423 CA (rs6505162), miR-449b AG (rs10061133) and miR-604 AG (rs2368393) monobasic polymorphism and repetition of Korean women Regarding the relationship between the risk of developing implantation failure, specifically miR-27a AG, miR-449b AG and miR-604 from the DNA sample of the subject to provide information necessary for predicting the risk of repetitive implantation failure in Korean women. It relates to a method and a kit therefor, characterized in that the single base polymorphism selected from AG is determined, or the miR-423 CA single base polymorphism is further determined. According to the present invention, repetition of Korean women by discriminating a single nucleotide polymorphism selected from miR-27a AG, miR-449b AG, and miR-604 AG, or further discriminating miR-423 CA monobasic polymorphism It can provide very useful information for predicting the risk of developing implantation failure. In particular, when the kit of the present invention using the monobasic polymorphism is used, the above information can be more easily provided.
展开▼
机译：关于韩国女性的miR-27a A> G（rs895819），miR-423 C> A（rs6505162），miR-449b A> G（rs10061133）和miR-604 A> G（rs2368393）韩国女性的单态多态性和重复性受试者DNA样本中发生植入失败风险的风险之间的关系，特别是miR-27a A> G，miR-449b A> G和miR-604，以提供预测韩国女性重复植入失败风险的必要信息。本发明涉及一种方法及其试剂盒，其特征在于，确定选自A> G的单碱基多态性，或进一步确定miR-423C>单碱基多态性。根据本发明，通过区分选自miR-27a A> G，miR-449b A> G和miR-604 A> G的单核苷酸多态性或进一步区分miR-423 C> A一元性来重复韩国女性。多态性它可以为预测植入失败的风险提供非常有用的信息。特别地，当使用使用一元多态性的本发明的试剂盒时，可以更容易地提供上述信息。
展开▼
