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Compositions and methods for treating peripheral T-cell lymphoma and cutaneous T-cell lymphoma

机译:治疗外周T细胞淋巴瘤和皮肤T细胞淋巴瘤的组合物和方法

摘要

The present invention provides dual selective PI3K delta and gamma protein kinase inhibitors, such as (S)-2-(1-((9H-purine), for the treatment of peripheral T-cell lymphoma (PTCL) and cutaneous T-cell lymphoma (CTCL). -6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one (compound (A), also known as tenalisib) or a pharmaceutically acceptable salt thereof, Or to the use of pharmaceutical compositions containing such inhibitors.
机译:本发明提供了双重选择性PI3Kδ和γ蛋白激酶抑制剂,例如(S)-2-(1-((9H-嘌呤)),用于治疗外周T细胞淋巴瘤(PTCL)和皮肤T细胞淋巴瘤。 (CTCL).- 6-基)氨基)丙基)-3-(3-氟苯基)-4H-铬-4-(化合物(A),也称为替尼西布)或其药学上可接受的盐,或含有此类抑制剂的药物组合物的用途。

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