首页> 外国专利> METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE USING AN L-LYSINE EXCRETING BACTERIUM OF THE SPECIES CORYNEBACTERIUM GLUTAMICUM HAVING A COMPLETELY OR PARTLY DELETED WHIB4 GENE

METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE USING AN L-LYSINE EXCRETING BACTERIUM OF THE SPECIES CORYNEBACTERIUM GLUTAMICUM HAVING A COMPLETELY OR PARTLY DELETED WHIB4 GENE

机译：利用具有完全或部分缺失的WhiB4基因的谷氨酸棒状杆菌属细菌分泌的L-赖氨酸细菌发酵生产L-赖氨酸的方法

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摘要

The present invention essentially relates to a method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted whiB4 gene.

机译：本发明主要涉及使用具有完全或部分缺失的 whiB4 基因的谷氨酸棒状杆菌种的L-赖氨酸排泄细菌发酵生产L-赖氨酸的方法。。 展开▼

著录项

公开/公告号WO2020109367A1

专利类型

公开/公告日2020-06-04

原文格式PDF

申请/专利权人 EVONIK OPERATIONS GMBH;
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申请/专利号WO2019EP82697

发明设计人 THIERBACH GEORG;SCHNEIDER FRANK;VOSS KORNELIA;BEKEL THOMAS;
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申请日2019-11-27

分类号C12P13/08;

国家 WO

入库时间 2022-08-21 11:10:56

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1. 使用具有完全或部分缺失的whiB4基因的物种谷氨酸棒杆菌的L-赖氨酸分泌细菌发酵生产L-赖氨酸的方法 [P] . 中国专利： CN113166787A . 2021-07-23

2. 具有L-赖氨酸生产能力的棒状杆菌属微生物及利用其生产L-赖氨酸的方法 [P] . 中国专利： CN108138191B . 2021.10.15

3. METHOD FOR THE FERMENTATIVE PRODUCTION OF L-LYSINE USING AN L-LYSINE EXCRETING BACTERIUM OF THE SPECIES CORYNEBACTERIUM GLUTAMICUM HAVING A COMPLETELY OR PARTLY DELETED WHIB4 GENE [P] . EP3887533A1 . 2021-10-06

机译：使用L-赖氨酸排泄细菌的L-赖氨酸发酵生产的方法，该物种具有完全或部分缺失的WHIB4基因的棒状谷氨酰胺

4. Method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted WHIB4 gene [P] . US11198895B2 . 2021-12-14

机译：使用L-赖氨酸排泄细菌的L-赖氨酸发酵生产的方法，该物种具有完全或部分缺失的WHIB4基因的棒状谷氨酰胺

5. - - Corynebacterium glutamicum deleted a gene msmA encoding methylmalonate-semialdehyde dehydrogenase and method for producing L-lysine using the same [P] . 韩国专利： KR100798118B1 . 2008-01-28

机译： --谷氨酸棒杆菌删除了编码丙二酸甲酯-半醛脱氢酶的msmA基因及其生产L-赖氨酸的方法

1. L-Lysine production independent of the oxidative pentose phosphate pathway by Corynebacterium glutamicum with the Streptococcus mutans gapN gene [J] . Takeno Seiki, Hori Kazumasa, Ohtani Sachiko, Metabolic engineering . 2016,第Null期

2. L-Lysine production independent of the oxidative pentose phosphate pathway by Corynebacterium glutamicum with the Streptococcus mutans gapN gene [J] . Takeno Seiki, Hori Kazumasa, Ohtani Sachiko, Metabolic engineering . 2016,第Null期

3. Improvement of cell growth and l-lysine production by genetically modified Corynebacterium glutamicum during growth on molasses [J] . Xu Jianzhong, Zhang Junlan, Guo Yanfeng, Journal of industrial microbiology & biotechnology . 2013,第12期

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5. Fermentative Production of l-2-Hydroxyglutarate by Engineered Corynebacterium glutamicum via Pathway Extension of l-Lysine Biosynthesis [O] . Carina Prell, Arthur Burgardt, Florian Meyer, 2020

6. Transcriptome and Gene Ontology (GO) Enrichment Analysis Reveals Genes Involved in Biotin Metabolism That Affect l-Lysine Production in Corynebacterium glutamicum [O] . Hong-Il Kim, Jong-Hyeon Kim, Young-Jin Park 2016

1. 微生物发酵法生产L-赖氨酸的研究进展 [C] . XU Jian-zhong ,徐建中 ,ZHANG Wei-guo . 全国氨基酸研究开发暨综合应用新技术新设备交流研讨会 . 2011

2. 利用重组大肠杆菌和核糖开关进行L-赖氨酸生产的研究 [A] . 王俊明 . 2015