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METHODS, SYSTEMS AND COMPOSITIONS FOR THE NOVEL USE OF ENTEROBACTIN TO TREAT IRON DEFICIENCY AND RELATED ANEMIA

机译:新型肠抑菌素治疗铁缺乏症和相关性贫血的方法,系统和组合物

摘要

In one embodiment, the invention relates to the use of enterobactin (Ent), and/or Ent analogs as a therapeutic agent to treat iron deficiency and its related anemia. In a preferred embodiment, Ent and/or Ent analogs may be delivered to a host organism, such as a human subject to treat an iron-related disease condition. In such an embodiment, Ent and/or Ent analogs may be delivered to a human subject in need thereof through a pharmaceutical compositions and/or through a genetically engineered bacteria, or probiotic organism.
机译:在一个实施方案中,本发明涉及肠抑素(Ent)和/或Ent类似物作为治疗铁缺乏症及其相关贫血的治疗剂的用途。在一个优选的实施方案中,可以将Ent和/或Ent类似物递送至宿主生物,例如人类,以治疗铁相关的疾病。在这样的实施方案中,可以通过药物组合物和/或通过基因工程细菌或益生生物将Ent和/或Ent类似物递送至需要其的人类受试者。

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