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Application of Ilexgenin O in preparation of medicament for preventing and treating senile dementia

机译：冬凌草甲素O在制备防治老年性痴呆药物中的应用

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摘要

The present invention discloses an application of ilexgenin O in a preparation of a medicament for preventing and treating senile dementia. Alzheimer's disease is a disease mainly characterized by primary and progressive degenerative diseases of the central nervous system with clinical manifestation of irreversible deterioration of cognitive and memory functions, mainly due to the neuron damage caused by excessive Ap deposits in the brain. The present invention finds that ilexgenin O can prevent nerve cell damage caused by Ap, and thus has the prospect of being developed into an anti-senile dementia drug.

机译：本发明公开了冬青素O在制备用于预防和治疗老年性痴呆的药物中的应用。阿尔茨海默氏病是一种主要以中枢神经系统原发性和进行性退行性疾病为特征的疾病，其临床表现是认知和记忆功能不可逆转的恶化，这主要归因于大脑中过多的Ap沉积引起的神经元损伤。本发明发现冬青素O可以预防由Ap引起的神经细胞损伤，因此具有被开发成抗衰老性痴呆药的前景。

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公开/公告号LU101639B1

专利类型
公开/公告日2020-06-15

原文格式PDF
申请/专利权人 HENAN UNIVERSITY OF CHINESE MEDICINE;
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申请/专利号LU20190101639
发明设计人 ZHANG ZHENQIANG;YUAN YONG;XIE ZHISHEN;SONG JUNYING;JIANG YALI;WANG PAN;ZHENG HUAHUI;SUN LIMIN;SU YUNFANG;ZHANG JUNXIA;LI ZHONGHUA;MA JINLIAN;ZHAO JIANPING;GAO GAI;
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申请日2019-11-19
分类号A61P25/28;
国家 LU
入库时间 2022-08-21 11:17:02

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