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28 kda gst proteins from schistosoma for the use thereof in the treatment of inflammatory autoimmune disease generating a th1 and/or th17 response

机译：来自血吸虫的28 kda gst蛋白，用于治疗产生th1和/或th17反应的炎性自身免疫疾病

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摘要

The present invention relates to a product selected from a protein, a fragment of the protein, a derived sequence and a homologous sequence of the protein, the protein including or being constituted by the 28 kDa glutathione S-transferase protein from a schistosome selected from Schistosoma haematobium, Schistosoma mansoni, Schistosoma bovis represented respectively by the sequences SEQ ID NO: 1, SEQ ID NO: 2 and SEQ ID NO: 3 for the use thereof in the treatment of an inflammatory autoimmune disease generating a response of type Th1 and/or Th17.

机译：本发明涉及选自蛋白质，蛋白质的片段，蛋白质的衍生序列和同源序列的产物，该蛋白质包括来自血吸虫病的血吸虫病的28kDa谷胱甘肽S-转移酶蛋白质或由其构成。分别由序列SEQ ID NO：1，SEQ ID NO：2和SEQ ID NO：3表示的嗜血杆菌，曼氏血吸虫，牛血吸虫，用于治疗产生Th1和/或Th1型应答的炎性自身免疫疾病Th17。

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公开/公告号IL233876A

专利类型
公开/公告日2020-04-30

原文格式PDF
申请/专利权人 CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE;UNIVERSITE DU DROIT ET DE LA SANTE DE LILLE 2;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);
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申请/专利号IL20140233876
发明设计人
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申请日2014-07-30
分类号A61K38/45;A61K39;A61K39/002;C07K14;C12N9/10;
国家 IL
入库时间 2022-08-21 11:17:20

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