首页> 外国专利> METHODS FOR TREATING CANCER IN A PATIENT AND A HEMATOLOGICAL MALIGNITY, FOR EXPANDING TUMOR INFILTRANT LYMPHOCYTES, PERIPHERAL BLOOD LYMPHOCYTES AND INFILTRANT SPRAY LYMPHOCYTES, PROCEDURE FOR THE PREPARATION OF A POPULATION IN THE MANUFACTURE OF A POPULATION OF TUMOR INFILTRANT LYMPHOCYTES.

METHODS FOR TREATING CANCER IN A PATIENT AND A HEMATOLOGICAL MALIGNITY, FOR EXPANDING TUMOR INFILTRANT LYMPHOCYTES, PERIPHERAL BLOOD LYMPHOCYTES AND INFILTRANT SPRAY LYMPHOCYTES, PROCEDURE FOR THE PREPARATION OF A POPULATION IN THE MANUFACTURE OF A POPULATION OF TUMOR INFILTRANT LYMPHOCYTES.

机译：治疗患者和血液系统恶性肿瘤的方法，用于扩展肿瘤感染性淋巴细胞，外周血淋巴细胞和感染性喷雾淋巴细胞的方法，用于制备制造过程中人口总数的方法。

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摘要

methods of expanding tumor infiltrating lymphocytes (tils), including peripheral blood lymphocytes and bone marrow infiltrating lymphocytes, from the blood and / or bone marrow of patients with hematological malignancies, such as liquid tumors, including lymphomas and leukemias, and uses of such expanded tils in the treatment of diseases, such as cancers and hematological malignancies, are disclosed here.

机译：从血液恶性肿瘤（例如液体肿瘤，包括淋巴瘤和白血病）的患者的血液和/或骨髓中扩增包括外周血淋巴细胞和骨髓浸润淋巴细胞在内的肿瘤浸润淋巴细胞（tils）的方法，以及此类扩增tils的用途本文公开了在诸如癌症和血液恶性肿瘤等疾病的治疗中的用途。

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公开/公告号BR112019023409A2

专利类型
公开/公告日2020-06-16

原文格式PDF
申请/专利权人 IOVANCE BIOTHERAPEUTICS INC.;
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申请/专利号BR20191123409
发明设计人 LAVAKUMAR KARYAMPUDI;MARIA FARDIS;
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申请日2018-05-10
分类号C12N5/0781;A61K35/17;C12N5/0783;
国家 BR
入库时间 2022-08-21 11:18:23

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