首页> 外国专利> Adaptation of Hollow-Fiber-Based Cell Culture Technology for the Manufacturing of (1) Neo-Islets, Employed for the Treatment of Type 1 and Type 2 Diabetes Mellitus, and (2) the Generation of Exosomes from Various Cell Types, Used in the Treatment of Different Organ Injuries and Diseases

Adaptation of Hollow-Fiber-Based Cell Culture Technology for the Manufacturing of (1) Neo-Islets, Employed for the Treatment of Type 1 and Type 2 Diabetes Mellitus, and (2) the Generation of Exosomes from Various Cell Types, Used in the Treatment of Different Organ Injuries and Diseases

机译：基于空心纤维的细胞培养技术在制造（1）用于治疗1型和2型糖尿病的新胰岛和（2）从各种细胞类型产生外泌体方面的适应性研究不同器官损伤和疾病的治疗

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摘要

Disclosed herein is a method of generating exosomes (extracellular nanovesicles) and/or neo-islets from mesenchymal or adipose stem cells or islets, or other cells in a Hollow-Fiber-based Cell Expansion (HFCE) System. Such exosomes and/or neo-islets may be used for the treatment of T1DM, T2DM, or associated microvascular disease.

机译：本文公开了从基于中空纤维的细胞扩增（HFCE）系统中的间充质或脂肪干细胞或胰岛或其他细胞产生外泌体（细胞外纳米囊泡）和/或新胰岛的方法。此类外泌体和/或新胰岛可用于治疗T1DM，T2DM或相关的微血管疾病。

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公开/公告号US2020208115A1

专利类型
公开/公告日2020-07-02

原文格式PDF
申请/专利权人 SYMBIOCELLTECH LLC;
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申请/专利号US201816646112
发明设计人 CHRISTOF WESTENFELDER;ANNA L. GOOCH;
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申请日2018-09-07
分类号C12N5/0775;C12M1;C12N5/071;A61P3/10;
国家 US
入库时间 2022-08-21 11:22:26

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