首页> 外国专利> METHOD FOR PREPARATION OF HIGHLY POLARIZED NUCLEAR SPINS CONTAINING SAMPLES AND USES THEREOF FOR NMR AND MRI

METHOD FOR PREPARATION OF HIGHLY POLARIZED NUCLEAR SPINS CONTAINING SAMPLES AND USES THEREOF FOR NMR AND MRI

机译:含样品的高极化核小分子的制备方法及其用于NMR和MRI的研究

摘要

A method tor the preparation of a highly polarized nuclear spins containing sample of an organic or inorganic material, containing H or OH groups or adsorbed water molecules. Such highly polarized nuclear spins containing samples can be subjected to nuclear magnetic resonance (NMR) measurement and/or can be thawed and immediately administered to an individual undergoing a magnetic resonance imaging (MRI) scan. The method is based on generating unstable radicals on the surface of the sample in the presence of ionized environment followed by cooling the sample to cryogenic temperatures. A device for carrying out a particular step of said method is also discloses.
机译:一种制备高度极化的核自旋的方法,该核自旋包含含有H或OH基团或吸附的水分子的有机或无机材料样品。可以对包含样品的这种高度极化的核自旋进行核磁共振(NMR)测量和/或可以将其解冻并立即给予经历磁共振成像(MRI)扫描的个体。该方法基于在存在电离环境的情况下在样品表面产生不稳定的自由基,然后将样品冷却至低温。还公开了用于执行所述方法的特定步骤的设备。

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