首页> 外国专利> SUSTAINED-RELEASE 9-CIS RETINOIC ACID IMPLANTABLE DRUG DELIVERY PELLETS FOR THE PREVENTION OF POSTSURGICAL EDEMA AND LYMPHEDEMA

SUSTAINED-RELEASE 9-CIS RETINOIC ACID IMPLANTABLE DRUG DELIVERY PELLETS FOR THE PREVENTION OF POSTSURGICAL EDEMA AND LYMPHEDEMA

机译:持续释放的9-CIS视黄酸可植入药物颗粒预防手术后水肿和淋巴水肿

摘要

A method of treating post-surgical edema includes a step of administering an effective amount of a pharmaceutical composition to a subject identified a risk of post-surgical edema. The pharmaceutic composition include a retinoic acid component selected from the group consisting of 9-cis retinoic acid, geometric isomers of 9-cis retinoic acid, metabolites of 9-cis retinoic acid, substituted derivatives thereof, and combinations thereof. An implantable pellet including the retinoic acid component is also provided.
机译:一种治疗手术后水肿的方法,包括对确定了手术后水肿风险的受试者给予有效量的药物组合物的步骤。该药物组合物包含选自9-顺式视黄酸的视黄酸组分,9-顺式视黄酸的几何异构体,9-顺式视黄酸的代谢物,其取代的衍生物及其组合。还提供了包含视黄酸成分的可植入丸剂。

著录项

  • 公开/公告号US2020337991A1

    专利类型

  • 公开/公告日2020-10-29

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF SOUTHERN CALIFORNIA;

    申请/专利号US202016857927

  • 发明设计人 ALEX K. WONG;YOUNG-KWON HONG;

    申请日2020-04-24

  • 分类号A61K9;A61K31/203;A61K47/06;

  • 国家 US

  • 入库时间 2022-08-21 11:23:48

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