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Oxo-M and 4-PPBP induction of tenogenic differentiation of perivascular tendon stem cells
Oxo-M and 4-PPBP induction of tenogenic differentiation of perivascular tendon stem cells
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机译:Oxo-M和4-PPBP诱导血管周肌腱干细胞腱向分化
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摘要
Provided herein are compositions including oxotremorine (e.g., oxotremorine methiodide or Oxo-M) and 4-PPBP (e.g., 4-PPBP maleate). Also provided are methods of treating a connective tissue defect in a subject with oxotremorine and 4-PPBP. In addition, provided are scaffolds and methods of making same that include multiple fibers that include Oxo-M, 4-PPBP, and optionally icariin or kartogenin.
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