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ANIMAL MODEL FOR GENERATING A STEREOTYPE OF FOCAL ONSET SEIZURES

机译:产生局灶性发作定型的动物模型

摘要

It includes the steps of (1) preparing step; (2) anesthetizing step; (3) electrodes installing step; and (4) focal onset seizures inducing step. First, a live animal is anesthetized. The electrodes are installed on a working zone of its brain. A first chemical liquid is injected beneath the cerebral cortex of this animal. At two different times, a first electric stimulation and a second electric stimulation are activated by the controller respectively so as to generate a first and a second focal onset seizure accordingly. Thus, it can generate focal onset seizures. It is easy to change the electric stimulation position, numbers and type. In addition, the survival rate of a larger-sized animal after anesthesia is higher.
机译:它包括步骤(1)准备步骤; (2)麻醉步骤; (3)电极安装步骤; (4)局部发作性癫痫发作诱导步骤。首先,将活体动物麻醉。电极安装在其大脑的工作区域上。将第一化学液体注入该动物的大脑皮层下方。在两个不同的时间,控制器分别激活第一电刺激和第二电刺激,以相应地产生第一和第二局灶发作。因此,它可以引起局灶性发作。改变电刺激位置,数量和类型很容易。此外,麻醉后大型动物的存活率更高。

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