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Immunoassay for S-adenosylmethionine using S-adenosylmethionine analog and personalized therapy

机译:使用S-腺苷甲硫氨酸类似物和个性化疗法进行S-腺苷甲硫氨酸的免疫测定

摘要

PROBLEM TO BE SOLVED: To provide a method for detecting the presence or absence of a disease associated with a decreased level of S-adenosylmethionine in a patient. A method of identifying a patient suspected of having a disease or at risk of having a disease, obtaining a biological sample from the patient, and using an antibody derived from a hapten analog of S-adenosylmethionine Determining the level of S-adenosylmethionine in said biological sample and associating the level of S-adenosylmethionine with the presence or absence of disease. The present invention also provides a method for measuring SAH used for calculating a methylation index (ratio of SAM/SAH in body fluid) which is an index of an individual's health condition. [Selection diagram] None
机译:要解决的问题:提供一种检测患者中是否存在与S-腺苷甲硫氨酸水平降低有关的疾病的方法。一种鉴定疑似患有疾病或有患疾病风险的患者的方法,从该患者获得生物学样品,并使用衍生自S-腺苷甲硫氨酸半抗原类似物的抗体确定所述生物制剂中S-腺苷甲硫氨酸的水平样本,并将S-腺苷甲硫氨酸的水平与疾病的有无相关联。本发明还提供一种用于测量SAH的方法,该SAH用于计算甲基化指数(体液中SAM / SAH的比率),该甲基化指数是个人健康状况的指标。 [选择图]无

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