首页> 外国专利> POLYMETHYLMETHACRYLATE BONE CEMENT WITH ADJUSTABLE INITIAL VISCOSITY AND A METHOD FOR PRODUCING A BONE CEMENT PASTE WITH VARIABLE INITIAL VISCOSITY

POLYMETHYLMETHACRYLATE BONE CEMENT WITH ADJUSTABLE INITIAL VISCOSITY AND A METHOD FOR PRODUCING A BONE CEMENT PASTE WITH VARIABLE INITIAL VISCOSITY

机译:具有可调节的初始粘度的聚甲基丙烯酸甲酯骨水泥和制备具有不同的初黏度的骨水泥糊的方法

摘要

A polymerizable polymethylmethacrylate bone cement, in which the initial viscosity of the cement dough can be controlled. The polymerizable bone cement composition comprises a monomer for radical polymerization, a powdered polymethylmethacrylate-co-polymer soluble in the monomer or a mixture comprising polymethylmethacrylate-co-polymers, a polymerization initiator, and a radiopaquer, wherein the powdered polymethylmethacrylate-co-polymer comprises at least one particulate polymethylmethacrylate-co-polymer having a molar mass of more than or equal to 200,000 g/mol, and the polymethylmethacrylate-co-polymer is obtainable by polymerization of a mixture of 90.0% or more by weight methylmethacrylate and 10.0% or less by weight of one or more comonomers, wherein the weight ratio of component A comprising the polymethylmethacrylate-co-polymer, radiopaquer, and polymerization initiator, and component B comprising a monomer for radical polymerization, stabilizer, and polymerization accelerator, is approximately 2.0 to 3.4 to 1.0, for controlling the initial viscosity of the bone cement dough formed by mixing components A and B.
机译:一种可聚合的聚甲基丙烯酸甲酯骨水泥,其中可以控制水泥面团的初始粘度。所述可聚合骨水泥组合物包含用于自由基聚合的单体,可溶于所述单体的粉末状聚甲基丙烯酸甲酯共​​聚物或包含聚甲基丙烯酸甲酯共​​聚物的混合物,聚合引发剂和不透射线,其中所述粉末状聚甲基丙烯酸甲酯共​​聚物包括:至少一种摩尔质量大于或等于200,000 g / mol的聚甲基丙烯酸甲酯共​​聚物,并且该聚甲基丙烯酸甲酯共​​聚物可以通过将90.0重量%以上的甲基丙烯酸甲酯和10.0%或更高的混合物进行聚合而获得。按重量计约一种或多种共聚单体,其中包含聚甲基丙烯酸甲酯共​​聚物,不透射线和聚合引发剂的组分A与包含用于自由基聚合的单体,稳定剂和聚合促进剂的组分B的重量比约为2.0至3.4至1.0,用于控制通过混合组合物形成的骨水泥生面团的初始粘度节点A和B。

著录项

  • 公开/公告号EP3141267B1

    专利类型

  • 公开/公告日2019-11-20

    原文格式PDF

  • 申请/专利权人 HERAEUS MEDICAL GMBH;

    申请/专利号EP20160187651

  • 发明设计人 VOGT SEBASTIAN;KLUGE THOMAS;

    申请日2016-09-07

  • 分类号A61L24/04;

  • 国家 EP

  • 入库时间 2022-08-21 11:40:45

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