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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Influence of initial component temperature on the apparent viscosity and handling characteristics of acrylic (PMMA) bone cement.
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Influence of initial component temperature on the apparent viscosity and handling characteristics of acrylic (PMMA) bone cement.

机译：初始组分温度对丙烯酸（PMMA）骨水泥的表观粘度和处理特性的影响。

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摘要

The flow and polymerization characteristics of poly(methylmethacrylate) (PMMA) bone cement can be changed by manipulating the temperature of the bone cement components or the environment that they are prepared in. To quantify the effects of the initial component temperature (T(ic)) of acrylic bone cement on the rheological and handling characteristics, ASTM F451-99a compliant methods and clinically relevant testing methods were utilized. A rheometer was designed and fabricated using the dimensions of a clinical, commercially available, cement gun and nozzle. The influence on the apparent viscosity and handling characteristics (setting time, working time, and peak exotherm temperature) for a high viscosity (HV) commercially-available acrylic bone cement, Palacos R, were determined. The values of T(ic) used were 23 degrees C (room), 6 degrees C (refrigerator), and -14 degrees C (freezer). Using the apparent viscosity of a medium viscosity (MV) bone cement as a benchmark (Simplex P at room temperature), it was found that by adjusting the T(ic) the HV cement was able to mimic the flow characteristics of the MV cement. Lowering the T(ic) lowered the apparent viscosity of the bone cement. The effects of T(ic) on the polymerization of bone cement were studied in dynamic and static conditions. The dynamic test recorded temperature and torque from stirring resistance. Setting times were also determined using the ASTM exotherm mold method. The setting times determined by the dynamic testing conditions were consistently shorter than those determined by the ASTM method. Lowering the T(ic) increased the working and setting times; however, it did not have a significant effect on the peak exotherm temperature.
机译：聚甲基丙烯酸甲酯（PMMA）骨水泥的流动和聚合特性可以通过控制骨水泥组分的温度或制备它们的环境来改变。以量化初始组分温度（T（ic））的影响）丙烯酸类骨水泥的流变和处理特性，采用符合ASTM F451-99a的方法和临床相关的测试方法。流变仪是使用临床上可购得的水泥枪和喷嘴的尺寸设计和制造的。确定了对市售高粘度（HV）丙烯酸丙烯酸骨水泥Palacos R对表观粘度和处理特性（凝结时间，工作时间和放热峰值温度）的影响。使用的T（ic）值为23摄氏度（室温），6摄氏度（冰箱）和-14摄氏度（冰箱）。使用中等粘度（MV）骨水泥的表观粘度作为基准（室温下的Simplex P），发现通过调节T（ic），HV水泥能够模拟MV水泥的流动特性。降低T（ic）会降低骨水泥的表观粘度。在动态和静态条件下研究了T（ic）对骨水泥聚合的影响。动态测试记录了搅拌阻力产生的温度和扭矩。还使用ASTM放热模具方法确定凝固时间。通过动态测试条件确定的凝结时间始终比通过ASTM方法确定的凝结时间短。降低T（ic）会增加工作和凝固时间;但是，它对放热峰温度没有显着影响。

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