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MARKER GENES FOR COLORECTAL CANCER CLASSIFICATION, METHOD FOR JUDGING LYMPH NODE METASTASIS FOR PROGNOSIS OF COLORECTAL CANCER AND KIT THEREFOR

机译:大肠癌分类的标记基因,判断大肠癌预后的淋巴结转移的方法及其套件

摘要

A group of molecular biomarkers having the genes SLC35D3, POSTN, KLK6 and MUC2 can be used in objective and quantitative methods for the classification, prediction of prognosis and for guiding treatment decisions of a subject with colorectal cancer. More specifically, a method for determining the metastatic potential and/or tumor aggressiveness of a colorectal cancer in a subject can include determining the gene expression levels of genes SLC35D3, POSTN, KLK6 and/or MUC2 in a regional lymph node, a primary intestinal tumor, blood, or feces sample obtained from the subject.
机译:一组具有基因SLC35D3,POSTN,KLK6和MUC2的分子生物标志物可用于客观和定量方法,以分类,预测预后并指导大肠癌患者的治疗决策。更具体地,用于确定受试者中结肠直肠癌的转移潜力和/或肿瘤侵袭性的方法可以包括确定区域性淋巴结,原发性肠肿瘤中SLC35D3,POSTN,KLK6和/或MUC2的基因的表达水平。 ,血液或粪便样本。

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