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Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor

机译:结直肠癌分类的标记基因,判断淋巴结转移的方法,以了解结直肠癌和套件的预后

摘要

A group of molecular biomarkers having the genes SLC35D3, POSTN, KLK6 and MUC2 can be used in objective and quantitative methods for the classification, prediction of prognosis and for guiding treatment decisions of a subject with colorectal cancer. More specifically, a method for determining the metastatic potential and/or tumor aggressiveness of a colorectal cancer in a subject can include determining the gene expression levels of genes SLC35D3, POSTN, KLK6 and/or MUC2 in a regional lymph node, a primary intestinal tumor, blood, or feces sample obtained from the subject.
机译:具有基因SLC35D3,PARTN,KLK6和MUC2的一组分子生物标志物可用于客观和定量方法,用于分类,预测预测和具有结直肠癌的受试者的治疗决策。更具体地,用于确定对象中结肠直肠癌的转移性潜力和/或肿瘤侵蚀性的方法可以包括确定区域淋巴结中的基因SLC35D3,PARTN,KLK6和/或MUC2的基因表达水平,原发性肠肿瘤,从受试者获得的血液或粪便样品。

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