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Pharmaceutical component and use thereof for inhibiting the genesis and metastasis of a breast cancer tumor
Pharmaceutical component and use thereof for inhibiting the genesis and metastasis of a breast cancer tumor
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机译:药物成分及其在抑制乳腺癌肿瘤发生和转移中的用途
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摘要
The invention relates to a pharmaceutical component and the use thereof for inhibiting the genesis and metastasis of a breast cancer tumor, wherein the pharmaceutical component is a GR agonist comprising the ATA component of Antrodia cinnamomea as the principal active component and a pharmaceutically acceptable carrier or carrier Carrier comprises micro-ribonucleic acid-708 (miR-708) is activated by transcription and activation of the glucocorticoid receptor α (GR α) so that the proliferation of breast cancer cells is inhibited and a stagnation of their cell cycle is induced by the activated component signaling activates the expression of micro-ribonucleic acid-708 (miR-708) and then inhibits the viability of NF-κB and inhibits and regulates the expression of its downstream target genes COX-2 and cMYC.
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