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METHOD FOR DISCOVERING PHARMACOGENOMIC BIOMARKERS
METHOD FOR DISCOVERING PHARMACOGENOMIC BIOMARKERS
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机译:药理生物标志物的发现方法
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摘要
The present invention relates to a method for identifying a genomic pharmaceutical biomarker related to a different response (efficacy, side effects, and other end points) to a therapeutic agent. The present invention provides means for performing genome-wide association studies using archived clinical samples to identify novel genomic pharmaceutical biomarkers. The newly discovered biomarkers are then used to predict the drug response, to administer the drug only to those who will benefit, or to use a companion diagnostic test, which can help exclude subjects who may have side effects. Can be developed.
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