首页> 外国专利> 2 Visceral adipose tissue macrophage-targeted gene/carrier complex for preventing or treating obesity-induced type II diabetes

2 Visceral adipose tissue macrophage-targeted gene/carrier complex for preventing or treating obesity-induced type II diabetes

机译:2内脏脂肪组织巨噬细胞靶向基因/载体复合物,用于预防或治疗肥胖引起的II型糖尿病

摘要

The present invention relates to a visceral fat macrophage-targeted non-viral gene/carrier complex for preventing and treating obesity-derived type 2 diabetes. More specifically, a gene/carrier complex according to the present invention targets macrophages of visceral fat to stably deliver a therapeutic gene when injected into the body, thereby exhibiting an excellent TACE inhibitory effect. Therefore, the gene/carrier complex can be applied for preventing or treating obesity-derived type 2 diabetes.
机译:本发明涉及靶向内脏脂肪巨噬细胞的非病毒基因/载体复合物,用于预防和治疗由肥胖引起的2型糖尿病。更具体地,根据本发明的基因/载体复合物靶向内脏脂肪的巨噬细胞,以在注入体内时稳定地递送治疗性基因,从而表现出优异的TACE抑制作用。因此,该基因/载体复合物可以用于预防或治疗由肥胖引起的2型糖尿病。

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