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METHOD FOR PREPARING FUNCTIONAL LIVER PROGENITOR CELLS OR LIVER CELLS, OR PREPARING FUNCTIONAL SMALL-INTESTINAL EPITHELIAL PROGENITOR CELLS OR SMALL-INTESTINAL EPITHELIAL CELLS
METHOD FOR PREPARING FUNCTIONAL LIVER PROGENITOR CELLS OR LIVER CELLS, OR PREPARING FUNCTIONAL SMALL-INTESTINAL EPITHELIAL PROGENITOR CELLS OR SMALL-INTESTINAL EPITHELIAL CELLS
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机译:制备功能性肝祖细胞或肝细胞,或制备功能性小肠上皮细胞或小肠上皮细胞的方法
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摘要
Provided is a method for preparing functional liver (progenitor) cells or functional small-intestinal epithelial (progenitor) cells, said method comprising a step for culturing, in the presence of an antibiotic, an isolated cell population including liver (progenitor) cells or small-intestinal epithelial (progenitor) cells. Also provided is a substantially homogeneous isolated cell population including functional liver progenitor cells, wherein the expression of CYP3A4 in the functional liver progenitor cells is at least five times greater than the expression of the same in the HepaRG (registered trademark) cell line.
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