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Monitoring the effects of sleep deprivation using neuronal avalanches

机译:使用神经元雪崩监测睡眠剥夺的影响

摘要

#$%^&*AU2019202928A120190516.pdf#####ABSTRACT The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent (a) or branching parameter (u) from a predetermined value at rest, wherein the pre-determined value of a is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is -3/2 and the pre-determined value of a is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.
机译:#$%^&* AU2019202928A120190516.pdf #####抽象本发明针对一种连续监测神经元的方法受试者的雪崩,包括:(a)确定雪崩指数的偏差(a)或分支参数(u)从静止时的预定值开始,其中预先确定a的值是同步神经元活动和预定值是-3/2,并且预定值是相继的比率传播同步神经元活动,预定值为1;和(b)重复一次(a)一次或多次,以连续监测a中的神经元雪崩学科。本发明的特征还在于确定或监视程度的方法。受试者的睡眠剥夺,识别易患睡眠的受试者的方法疾病和诊断受试者睡眠障碍的方法。

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