首页> 外国专利> HISTONE H3 TRIMETHYLATED LYSINE-SPECIFIC MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF

HISTONE H3 TRIMETHYLATED LYSINE-SPECIFIC MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF

机译：组蛋白H3三甲基化赖氨酸特异的单克隆抗体或其抗原结合片段

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摘要

The purpose of the present invention is to provide a monoclonal antibody that functions even in a state of intracellular reduction. The problem can be solved by a monoclonal antibody containing a heavy-chain variable region domain comprising an amino acid sequence represented by SEQ ID NO: 1 of the present invention and a light-chain variable region domain comprising an amino acid sequence represented by SEQ ID NO: 2, or an antigen-binding fragment thereof.

机译：本发明的目的是提供甚至在细胞内还原状态下也起作用的单克隆抗体。该问题可以通过以下单克隆抗体来解决，该单克隆抗体含有包含本发明的SEQ ID NO：1所示的氨基酸序列的重链可变区结构域和包含SEQ ID NO：1的氨基酸序列的轻链可变区结构域。 NO：2或其抗原结合片段。

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公开/公告号WO2018225781A1

专利类型
公开/公告日2018-12-13

原文格式PDF
申请/专利权人 TOKYO INSTITUTE OF TECHNOLOGY;
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申请/专利号WO2018JP21688
发明设计人 KIMURA HIROSHI;SATO YUKO;OHI AKITO;KURUMIZAKA HITOSHI;KUJIRAI TOMOYA;OHKAWA YASUYUKI;
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申请日2018-06-06
分类号C07K16/18;C07K19;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/12;C12N15/09;G01N33/53;C12P21/08;
国家 WO
入库时间 2022-08-21 11:57:47

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