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PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE
PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE
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机译:急性期与带状疱疹相关的疼痛预防或治疗剂
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摘要
A P2X4 receptor antagonist such as paroxetine, a di-azepinedione derivative having the following formula (IX)is used as an agent for preventing or treating zoster-associated pain in acute phase:wherein R1 is hydrogen, a C1-8 alkyl group, or the like;each of R2 and R3 is hydrogen, a C1-8 alkyl group, orthe like;each of R4 and R5 is hydrogen or the like; andW is a five-membered or six-membered heterocyclicring optionally having one or more substituents and comprisingone to four nitrogen atoms as the members of thering.
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