首页>
外国专利>
METHOD FOR DETECTING OR MEASURING THE IMPACT OF A VIRAL VECTOR COMPOSITION ON EUKARYOTIC CELLS AND BIOMARKERS USED THEREOF
METHOD FOR DETECTING OR MEASURING THE IMPACT OF A VIRAL VECTOR COMPOSITION ON EUKARYOTIC CELLS AND BIOMARKERS USED THEREOF
展开▼
机译:检测或测量病毒载体成分对真核细胞及其生物标志物影响的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to methods and compositions for characterization of global cellular changes in response to introduction of viral vector compositions into target cells. It more particularly refers to a method for assessing the quality of a viral vector composition for a transgene transfer into target cells comprising measuring the expression level of at least one biomarker selected in the group consisting of CXCL2 and EREG and/or of at least one biomarker selected in the group consisting of ASPM, AURKB, CENPA, CENPF, CKS1B, E2F8, ERCC6L, FAM83D, KIFC1, MKI67, NEK2, NUSAP1, OIP5, PRC1, RRM2, SGOL1, SPC25, TOP2A and TTK.
展开▼