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anti-bst2 antibody

机译:不要等

摘要

human anti-bst2 antibody, method for its production and use, polynucleotide, vector, hybridoma and therapeutic agent The present invention relates to anti-bst2 antibodies that have been selected using, as an indicator, the binding between antibst2 antibodies and various variants. with sp / icing of human bst2 antigen. As a result, the present inventors have successfully obtained anti-bst2 antibodies that specifically recognize bst2d, which has been reported to be expressed at high levels in cancer cells. antibodies of the present invention specifically bind to cells expressing bst2d. Nonspecific antibody binding to non-target tissues, which results in decreased antibody concentration in the blood, can be prevented by using the antibodies of the present invention therapeutically. alternatively, the present invention provides diagnostic agents comprising an antibody of the present invention which specifically detects tissues expressing bst2d.
机译:人抗bst2抗体,其生产和使用方法,多核苷酸,载体,杂交瘤和治疗剂技术领域本发明涉及已经使用抗bst2抗体与各种变体之间的结合作为指示剂选择的抗bst2抗体。带有人bst2抗原的sp /糖衣。结果,本发明人成功地获得了特异性识别bst2d的抗bst2抗体,据报道,该bst2d在癌细胞中以高水平表达。本发明的抗体特异性结合表达bst2d的细胞。通过治疗性使用本发明的抗体,可以防止与非靶组织结合的非特异性抗体,该非特异性抗体导致血液中的抗体浓度降低。或者,本发明提供了包含本发明的抗体的诊断剂,所述抗体特异性地检测表达bst2d的组织。

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