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antibody that specifically binds to a region on human connective tissue growth factor, chimeric antibody, pharmaceutical composition, use of an antibody, polynucleotide pair, recombinant polynucleotide, and, microorganism
antibody that specifically binds to a region on human connective tissue growth factor, chimeric antibody, pharmaceutical composition, use of an antibody, polynucleotide pair, recombinant polynucleotide, and, microorganism
"isolated antibody or biologically active portion thereof, cell line, pharmaceutical composition, methods of neutralizing a biological activity of ctgf and treating or preventing a disorder associated with ctgf, chimeric antibody, drug, polynucleotide sequence, recombinant polynucleotide, and host cell" " The present invention relates to antibodies that bind to ctgf. antibodies are particularly directed to the ctgf regions involved in biological activities associated with fibrosis. The invention also relates to methods of using antibodies to treat disorders associated with ctgf including localized and systemic fibrotic disorders including those of the lung, liver, heart, skin, and kidney.
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