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method of treating or alleviating metabolic disorders using gastric inhibitor peptide (gipr) receptor binding proteins in combination with glp-1 agonists

机译：胃抑制剂肽（gipr）受体结合蛋白结合glp-1激动剂治疗或缓解代谢异常的方法

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摘要

Methods of treating metabolic disorders and disorders using a gipr polypeptide specific antigen binding protein are provided. In various embodiments, the disease or metabolic disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, and diabetic nephropathy. in certain embodiments, the antigen binding protein is administered in combination with a glp-1 receptor agonist.

机译：提供了使用gipr多肽特异性抗原结合蛋白治疗代谢疾病和疾病的方法。在各种实施方案中，该疾病或代谢紊乱是2型糖尿病，肥胖症，血脂异常，葡萄糖水平升高，胰岛素水平升高和糖尿病性肾病。在某些实施方案中，抗原结合蛋白与glp-1受体激动剂组合施用。

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公开/公告号BR112018012833A2

专利类型
公开/公告日2018-12-04

原文格式PDF
申请/专利权人 AMGEN INC.;
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申请/专利号BR20181112833
发明设计人 BRANDON C. P. CLAVETTE;CHRISTOPHER MURAWSKY;DARREN L. BATES;DAVID J. LLOYD;DONGHUI SHI;GLENN N. SIVITS JR.;IAN N. FOLTZ;JINGHONG WANG;JUNMING YIE;MURIELLE M. VENIANT-ELLISON;NEERAJ AGRAWAL;RENEE KOMOROWSKI;SHU-YIN HO;XIAOSHAN MIN;ZHULUN WANG;
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申请日2016-12-21
分类号A61K38/26;A61K39/395;A61P3/10;C07K16/28;
国家 BR
入库时间 2022-08-21 12:03:33

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