首页> 外国专利> isolated protein, pharmaceutical composition, methods for modulating an immune or inflammatory response in a subject, for treating an ir-17 mediated disorder in a subject and for preparing a recombinant protein, isolated nucleic acid, and recombinant host cell

isolated protein, pharmaceutical composition, methods for modulating an immune or inflammatory response in a subject, for treating an ir-17 mediated disorder in a subject and for preparing a recombinant protein, isolated nucleic acid, and recombinant host cell

机译：分离的蛋白质，药物组合物，在受试者中调节免疫或炎性反应，在受试者中治疗ir-17介导的疾病以及制备重组蛋白，分离的核酸和重组宿主细胞的方法

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摘要

Binding proteins, including non-naturally occurring and recombinantly modified proteins that bind to an IL-17R and including proteins having a mutated IL-17 cytokine sequence, methods of making such molecules and methods of using such molecules as therapeutic, prophylactic and diagnostic agents are provided.

机译：结合蛋白，包括与IL-17R结合的非天然存在的和重组修饰的蛋白，以及包括具有突变的IL-17细胞因子序列的蛋白，制备此类分子的方法以及使用此类分子作为治疗剂，预防剂和诊断剂的方法是提供。

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公开/公告号BR112012008444A2

专利类型
公开/公告日2019-09-24

原文格式PDF
申请/专利权人 ELEVEN BIOTHERAPEUTICS INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;
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申请/专利号BR20121108444
发明设计人 BRACKEN M. KING;CHRISTOPHER K.GARCIA;GREGORY JAMES SIECZKIEWICZ;LAUREN K. ELY;MICHAEL M. SCHMIDT;SASHANK REDDY;THOAMS M. BARNES;
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申请日2010-10-11
分类号A61K39/395;
国家 BR
入库时间 2022-08-21 12:03:52

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