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METHOD AND APPARATUS FOR PREVENTING OR TERMINATING EPILEPTIC SEIZURES

机译:预防或终止癫痫发作的方法和装置

摘要

A method and apparatus for preventing or terminating seizures, by stimulating a brain with at least two implanted electrodes, each implanted in a different one of at least two regions of the brain, with a frequency to emulate neuronal synchrony. Upon detecting a potential or actual seizure occurrence, the frequency is electrically applied to the brain upon the detection to preempt or terminate the potential or actual seizure occurrence. Parts in the brain, where brain electrical activity is being measured, that have the highest connectivity are determined by phase-locking coherence. The select subset of areas showing synchrony, i.e., only those with the highest coherence that will best permit inducing a large global synchrony, are stimulated to preempt or terminate the potential or actual seizure occurrence.
机译:一种通过用至少两个植入的电极刺激大脑来预防或终止癫痫发作的方法和装置,每个电极都以模拟神经元同步的频率植入每个大脑的至少两个区域的不同区域中。一旦检测到潜在的或实际的癫痫发作,就在检测到该频率时将其电施加到大脑以抢占或终止潜在的或实际的癫痫发作。大脑中测量大脑电活动的部分具有最高的连通性,这取决于锁相干的相干性。刺激显示同步性的区域的选定子集,即只有那些具有最高连贯性的区域,才能最好地诱导大的全局同步性,从而刺激它们抢先或终止潜在的或实际的癫痫发作。

著录项

  • 公开/公告号US2019321638A1

    专利类型

  • 公开/公告日2019-10-24

    原文格式PDF

  • 申请/专利权人 DAVID J. MOGUL;

    申请/专利号US201916379359

  • 发明设计人 DAVID J. MOGUL;

    申请日2019-04-09

  • 分类号A61N1/36;A61B5;

  • 国家 US

  • 入库时间 2022-08-21 12:11:51

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