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Dual-action compounds targeting adenosine A_2Areceptor and adenosine transporter for prevention and treatment of neurodegenerative diseases

机译：靶向腺苷A _{2A 受体和腺苷转运蛋白的双重作用化合物，用于神经退行性疾病的预防和治疗}

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The present invention provides therapeutic agents for preventing and treating neurodegenerative diseases. These agents synergistically target both the adenosine A_2Areceptor (A_2AR) and the equilibrative nucleoside transporter 1 (ENT1).

机译：本发明提供了用于预防和治疗神经退行性疾病的治疗剂。这些药物协同靶向腺苷A _{2A 受体（A _{2A R）和平衡核苷转运蛋白1（ENT1）。}}

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公开/公告号US10342818B2

专利类型
公开/公告日2019-07-09

原文格式PDF
申请/专利权人 ACADEMIA SINICA;
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申请/专利号US201514849782
发明设计人 YUN-LIAN LIN;YIJUANG CHERN;JIM-MIN FANG;JUNG-HSING LIN;NAI-KUEI HUANG;
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申请日2015-09-10
分类号A01N43/04;A61K31/70;A61K31/7076;C07H19/167;A61K31/706;A61K31/7064;
国家 US
入库时间 2022-08-21 12:13:57

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Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases

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Dual-action compounds targeting adenosine A_2Areceptor and adenosine transporter for prevention and treatment of neurodegenerative diseases