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Actuated valve or pump for microfluidic devices

机译:微流体装置的致动阀或泵

摘要

Systems and methods disclosed herein related to an apparatus including a fluid flow plate and a microfluidic valve assembly. The fluid flow plate includes a plurality of polymer layers that define a fluid flow passage through the microfluidic valve assembly. The microfluidic valve assembly includes a valve seat, a flexible membrane, a valve cavity, a valve head, and an actuator. The actuator is configured to selectively control pressure applied by the valve head to the flexible membrane, such that in a first actuator state the valve head depresses the flexible membrane into the valve cavity and into contact with the valve seat, thereby preventing fluid flow through the valve assembly, and in a second state, the valve head and the flexible membrane are retracted substantially out of the valve cavity allowing fluid to flow through the valve assembly. In various implementations, the valve seat and/or the flexible membrane include an elastomer layer.
机译:本文公开的系统和方法涉及一种包括流体流板和微流体阀组件的设备。流体流动板包括多个聚合物层,所述多个聚合物层限定了穿过微流体阀组件的流体流动通道。微流体阀组件包括阀座,柔性膜,阀腔,阀头和致动器。致动器构造成选择性地控制由阀头施加到柔性膜的压力,使得在第一致动器状态下,阀头将柔性膜压入阀腔并与阀座接触,从而防止流体流过阀芯。阀组件,并且在第二状态下,阀头和柔性膜基本上从阀腔中缩回,从而允许流体流过阀组件。在各种实施方式中,阀座和/或柔性膜包括弹性体层。

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