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USE OF A VACCINE TARGETING A CRYPTIC TERT EPITOPE, FOR TREATING CANCER IN A HLA-A*0201-POSITIVE PATIENT HAVING A NON-IMMUNOGENIC TUMOR EXPRESSING TERT
USE OF A VACCINE TARGETING A CRYPTIC TERT EPITOPE, FOR TREATING CANCER IN A HLA-A*0201-POSITIVE PATIENT HAVING A NON-IMMUNOGENIC TUMOR EXPRESSING TERT
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机译：使用疫苗靶向隐匿性睾丸瘤治疗具有非免疫原性表达表达的HLA-A * 0201阳性患者中的癌症
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摘要
The invention pertains to the use of a tumor vaccine composed of two peptides of nine amino acids - the WT cryptic TERT572 (RLFFYRKSV, SEQ ID No: 1) expressed by tumor cells and its optimized variant TERT572Y (YLFFYRKSV, SEQ ID No: 2) - for treating cancer in a HLA-A*0201-positive patient having a non-immunogenic tumor expressing TERT.
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机译：本发明涉及由两种九个氨基酸的肽组成的肿瘤疫苗的用途-肿瘤细胞表达的WT隐性TERT572（RLFFYRKSV，SEQ ID No：1）及其优化的变体TERT572Y（YLFFYRKSV，SEQ ID No：2） -用于在患有表达TERT的非免疫原性肿瘤的HLA-A * 0201阳性患者中治疗癌症。
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