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Cocultures of cumulus cells and embryos during in vitro fertilization procedures

机译：体外受精过程中卵丘细胞和胚胎的共培养

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摘要

The present invention relates generally to the fields of reproductive medicine. More specifically, the present invention relates to a novel human embryo co-culture system to improve human embryo growth in vitro and, consequently, increase pregnancy rates in infertile women undergoing in vitro fertilization (IVF) treatment. More particularly, the present invention relates to a method of growing an embryo to a blastocyst stage of development comprising the step of coculturing said embryo in the presence of a population of cumulus cells.

机译：本发明总体上涉及生殖医学领域。更具体地，本发明涉及一种新颖的人类胚胎共培养系统，其在体外改善人类胚胎的生长，并因此提高在接受体外受精（IVF）治疗的不育妇女中的妊娠率。更具体地，本发明涉及一种使胚胎生长到胚泡发育阶段的方法，该方法包括在大量卵丘细胞存在下将所述胚胎共培养的步骤。

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公开/公告号EP2603581B1

专利类型
公开/公告日2019-07-17

原文格式PDF
申请/专利权人 INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);UNIVERSITÉ DE MONTPELLIER;CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER;
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申请/专利号EP20110741581
发明设计人 HAMAMAH SAMIR;ASSOU SAID;
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申请日2011-08-11
分类号C12N5/073;C12N5/0735;A61D19;
国家 EP
入库时间 2022-08-21 12:31:35

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