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首页> 外国专利> METHOD FOR EFFICIENCY ESTIMATION OF NEOADJUVANT POLYCHEMOTHERAPY OF MALIGNANT BREAST TUMOUR

METHOD FOR EFFICIENCY ESTIMATION OF NEOADJUVANT POLYCHEMOTHERAPY OF MALIGNANT BREAST TUMOUR

机译：恶性乳腺癌新辅助化疗的疗效评估方法

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FIELD: medicine.;SUBSTANCE: invention refers to radio diagnostics, namely, ultrasound diagnostics, and can be used to evaluate the efficiency of neoadjuvant polychemotherapy (NAPCT) of malignant breast tumour. Tumour ultrasonography is carried out using a multifrequency linear sensor by scanning a breast tumour in the energy Doppler regime. Scanning is performed from points applied to the skin along 2 mutually perpendicular lines along the tumour boundary with 5-mm increment. Scanning is performed from each point in 2 mutually perpendicular planes. The quantitative processing of each of the obtained scans is carried out: the ratio of the number of coloured pixels and the total number of pixels is calculated for each scan. Then, the average value of the ratio for each plane and the average value of the ratio for both planes are calculated. The study is performed before and after the first course of NAPCT. With a decrease in the ratio value after the course of treatment by 32% or more compared to the value before treatment, the effect of NAPCT is estimated as positive. With a decrease in the ratio value by less than 32% or an increase in the ratio value, the absence of the effect of NAPCT is noted.;EFFECT: method allows to accurately assess the effectiveness of neoadjuvant polychemotherapy by investigating the dynamics of malignant breast tumour blood supply.;2 dwg, 3 ex
机译：技术领域本发明涉及放射诊断，即超声诊断，并且可以用于评估恶性乳腺肿瘤的新辅助多化学疗法（NAPCT）的效率。使用多频线性传感器通过在能量多普勒方案中扫描乳腺肿瘤来进行肿瘤超声检查。从沿着肿瘤边界的两条相互垂直的线以5毫米的增量从施加到皮肤的点进行扫描。从2个相互垂直的平面中的每个点进行扫描。对获得的每个扫描进行定量处理：为每个扫描计算彩色像素数与像素总数之比。然后，计算每个平面的比率的平均值和两个平面的比率的平均值。该研究是在NAPCT的第一个疗程之前和之后进行的。与治疗前的值相比，治疗后的比率值降低32％或更多，估计NAPCT的效果为阳性。当比率值降低不到32％或比率值增加时，注意到没有NAPCT的作用。;效果：该方法可通过研究恶性乳房的动力学来准确评估新辅助多化学疗法的有效性肿瘤血液供应。; 2 dwg，3前

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