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METHOD FOR BUILDING MODEL OF ANIMAL SUFFERING FROM NON-HUMAN MAMMAL OBESITY OR RELATED DISEASE AND USE THEREOF
METHOD FOR BUILDING MODEL OF ANIMAL SUFFERING FROM NON-HUMAN MAMMAL OBESITY OR RELATED DISEASE AND USE THEREOF
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机译:建立非人类哺乳动物肥胖或相关疾病动物模型的方法及其应用
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摘要
A method for preparing a model of an animal suffering from non-human mammal obesity or a related disease, comprising the following steps: (a) providing a cell of a non-human mammal, and inactivating a Glce gene in the cell, thereby obtaining a non-human mammal cell with an inactivated Glce gene; and (b) using the cell having an inactivated Glce gene obtained in step (a) to prepare and obtain a model of an animal suffering from Glce gene-inactivated obesity or a related disease. The animal model is an effective model for an animal suffering from obesity or a related disease, which may be used for researching diseases such as obesity, hyperlipidemia, hypertension, and diabetes, and may also be used for screening and testing experiments of specific drugs.
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