首页> 外国专利> day dihydropyrazolo compounds (1.5 -? 'pyrazin - (5h) - one and their use as modulators of metabotropic glutamate receptors and negative allosteric

day dihydropyrazolo compounds (1.5 -? 'pyrazin - (5h) - one and their use as modulators of metabotropic glutamate receptors and negative allosteric

机译:日二氢吡唑并合物(1.5-?“吡嗪-(5h)-一种及其作为代谢型谷氨酸受体和负变构调节剂的用途

摘要

the present invention relates to new derivatives of 6 - dihydropyrazolo [1.5 - (4) pyrazin (5h) - one used as a negative allosteric modulators of metabotropic receptor (nams) glutamate subtype 2 ("mglur2").the invention relates to pharmaceutical compositions comprising such as compounds, processes for the preparation of such compounds and such compositions.and the use of such compounds and such compositions for the prevention or treatment of disorders in which mglur2 is involved.
机译:本发明涉及6-二氢吡唑并[1.5-(4)吡嗪(5h)的新衍生物-一种用作代谢型受体(nams)谷氨酸亚型2的负变构调节剂(″ mglur2″)。本发明涉及包含此类化合物的药物组合物,此类化合物的制备方法和此类组合物以及此类化​​合物和此类组合物在预防或治疗涉及mglur2的疾病中的用途。

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