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Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders
Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders
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机译：用于补体激活的侧向流免疫测定法和用于补体相关疾病的即时评估的方法
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摘要
A method for treating an individual at risk for a complement-associated disorder is provided, the method including: (a) obtaining a sample of a body fluid from the individual; (b) measuring a complement activation level in the sample via a point-of-care lateral flow immunoassay; (c) correlating the complement activation level in the sample to a risk of a complement-associated disorder by comparing the complement activation level in the sample to a reference level in a control, wherein a deviation in complement activation level in the sample compared to the reference level in the control indicates the individual is at risk for a complement-associated disorder; (d) selecting a treatment for the individual, based on the correlating of step (c); and (e) treating the individual with the treatment selected in accordance with step (d). Lateral flow immunoassays for the qualitative and quantitative point-of-care detection of complement activation and a method of monitoring an individual suffering from a complement-associated disorder are also provided herein.
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